WHY PREKULAB?
From pioneering the use of large neutral amino acids in treatments for PKU to attending global conferences, Prekulab has been at the heart of phenylketonuria treatment for over 40 years.
WHY PREKULAB?
From pioneering the use of large neutral amino acids in treatments for PKU to attending global conferences, Prekulab has been at the heart of phenylketonuria treatment for over 40 years.
Pioneering PKU management
Prekulab’s mission is to improve the quality of PKU patients’ lives.
Established in 1970, the firm is a specialist in the field of PKU research and uses its substantial knowledge in the area to develop new solutions to help those affected by PKU and their families to lead as normal a life as possible.
Prekulab is a pioneer in the use of Large Neutral Amino Acids (LNAAs) which allow patients to eat a nearly normal diet. Prekulab makes five products, three using LNAAs (NeoPhe tablets and powder, plus PreKUnil tablets) and two using amino acid complexes (Avonil tablets and powder). Our LNNA products are clinically tested; tablets are developed by Prekulab with an advanced tablet-coating technique to make them easy to swallow, and are odour free and flavourless.
Prekulab’s team regularly attends PKU and metabolic disease conferences around the world and works with a strong network of global healthcare professionals to share knowledge and help make a difference in the life of people with PKU.
More information on Prekulab and its clinical research is available on the professionals page.
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NeoPhe Tablets and Powder










Our newest and most advanced LNAA product gives double protection from Phe, stopping it from entering the brain and also inhibiting entry to the blood. Clinically proven NeoPhe is available in odour and flavourless tablets and citrus-flavoured powder, and allows PKU patients to get up to 80% of their protein intake from a normal diet.
NeoPhe tablets NeoPhe powder
NeoPhe Tablets and Powder












Our newest and most advanced LNAA product gives double protection from Phe, stopping it from entering the brain and also inhibiting entry to the blood. Clinically proven NeoPhe is available in odour and flavourless tablets and citrus-flavoured powder, and allows PKU patients to get up to 80% of their protein intake from a normal diet.
NeoPhe tablets NeoPhe powderPreKUnil Tablets












This advanced product pioneered the use of LNAAs in the treatment of phenylketonuria. It has been successful for PKU patients for more than 30 years. It is clinically proven to reduce Phe transport across the blood-brain barrier. PreKUnil allows PKU patients to get up to 80% of their protein intake from a normal diet. It is also suitable for late-diagnosed and untreated PKU.
PreKUnil tablets

PreKUnil Tablets












This advanced product pioneered the use of LNAAs in the treatment of phenylketonuria. It has been successful for PKU patients for more than 30 years. It is clinically proven to reduce Phe transport across the blood-brain barrier. PreKUnil allows PKU patients to get up to 80% of their protein intake from a normal diet. It is also suitable for late-diagnosed and untreated PKU.
PreKUnil tablets
Avonil Tablets and Powder









A conventional method for the management of PKU, Avonil contains all essential amino acids except Phe, plus multiple vitamins and minerals. Tablets are formulated for easy swallowing, while the powder is mixed with water or juice to drink. Tablets and powder are suitable for all ages, including children and during pregnancy, and must be combined with a restricted diet.
Avonil tablets Avonil powder
Avonil Tablets and Powder









A conventional method for the management of PKU, Avonil contains all essential amino acids except Phe, plus multiple vitamins and minerals. Tablets are formulated for easy swallowing, while the powder is mixed with water or juice to drink. Tablets and powder are suitable for all ages, including children and during pregnancy, and must be combined with a restricted diet.
Avonil tablets Avonil powder